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1、Study:LinkBetweenAntidepressantsMiscarriagePregnancyisoftenfraughtwithcomplicationsnotleastfwomensufferingfromdepressionwhilecarryingachild:newresearchsuggeststhatwomenwhotakeantidepressantmedicationsduringpregnancymayha
2、veanincreasedriskofmiscarriage.ScientistsatUniversityofMontrealreptMondayintheCanadianMedicalAssociationJournalthatwomentakingthedrugsmostoftenprescribedtotreatdepressionanxietyincludingiveserotoninreuptakeinhibits(SSRIs
3、)serotoninnepinephrinereuptakeinhibits(SNRIs)theoldertricyclicshadasignificantlyhigherriskofmiscarriagethanamatchedcontrolgroupofwomenwhodidnottakeantidepressants.Thestudyisthefirstofitskindtoanalyzewhichantidepressantsw
4、hichdosesaremostlikelytobeassociatedwithspontaneousabtion.LedbyAnickBrardattheFacultyofPharmacyattheUniversityofMontrealtheresearchteamalsodocumentedthattwoSSRIsparoxetine(Paxil)venlafaxine(Effex)areassociatedwiththegrea
5、testrisk.BrardanalyzeddatafromapregnancyregistrythatsheestablishedinQuebecwhichcollectsrecdsonbirthsspontaneousabtionsoccurringinhospitalsintheCanadianprovince.Thestudyincluded69742womenfromtheregistry5124ofwhomhadhadacl
6、inicallythe68%increasecouldbewhollyattributabletounderlyingcauses.“Theeffectistoobig”shenotes“whileitmayexplainasmallptionitwouldn’texplainthetotalityoftheeffect.”Stillobstetriciansarenotreadytostopwritingpreionsfantidep
7、ressantsjustyet.Takentogetherresearchontherisksofusingantidepressantsmostotherpreiondrugsfexpectantmomstheirdevelopingbabiesislimitedofteninconsistent.Evidenceftherisksassociatedwithdepressiondrugshasbeenincreasinginrece
8、ntyearshoweverwithpaststudiesfindingalinkbetweenthemedicationsparticularlywhenusedduringthefirsttrimesterasmuchasasixfoldincreaseinlungheartothercongenitalbirthdefectsinnewbns.Brard’sstudyaddssolidevidencefanewriskfactbu
9、tbecauseitisanobservationalstudysaysDr.AlexVidaeffdirectofresearchinthedivisionofmaternalfetalmedicineatUniversityofTexasMedicalSchoolatHouston“Withthislevelofevidenceimmediatechangesinpracticemaybeilladvised.”Suchfindin
10、gsleavewomenwithdepressionfacingincreasinglycomplicatedtreatmentdecisionswhentheyarepregnantconsideringstartingafamily.AccdingtotheAmericanCongressofObstetriciansGynecologists(ACOG)depressionduringpregnancyiscommon:about
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