中藥莪術(shù)油介入治療原發(fā)性肝癌的臨床研究.pdf

1、廣州中醫(yī)藥大學(xué)碩士學(xué)位論文中藥莪術(shù)油介入治療原發(fā)性肝癌的臨床研究姓名：章瑩申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：中醫(yī)內(nèi)科學(xué)指導(dǎo)教師：程劍華20050401ClinicalResearchonInterventionalTherapywithZedoaryTurmericOil(ZTO)forPrimaryLiverCancerSpeciality：TraditionalChineseMedicineAuthor：SingZhangTutor：Jian

2、huaChengAbstract[background]Primarylivercancer(PLC)ismalignanttumorprimaryathepatocyteorepithelialcellsofbileductWecandetectthetraceofPLCintheancientliteraturesofTCM，itbelongstoGuzhung(Cirrhosisascites)，oanji，Zhengjia，Ji

3、ju(abdominalmass)，Huangdan(jaundice)、XietongetcItishighlymalignantandprognosisisbadItisshowedbythedatafromtheMinistryofPublicHealthin1995thatPL，Cstands441100，000ofmortalityratetakingthesecondplaceamongallofmalignanttumor

4、sAnearlierperiodoperationisstillthebesttreatmentplanHoweverthemajorityofthepatientswithPLCarealreadyinMiddle—advancedstagewhenfinallydiagnosedorcomplicatedbyCirrhosisofliverandmisstheiropportunityofresectionSince1981tran

5、scatheterartedalchemoembolization(TACE)wasInstputforwardbyKate，theinterventionaltherapybyfiverarteryinlocalcureistheheadtherapyofPLCmissingopportunityofresectiontherapyItisalreadyextensivelyusedforclinical，andtheeffectis

6、accurateSomeachievementsinstudyoftreatmentforPLCinTCMhavebeenmadeinelementaryandclinicalstudyItisverydifficulttoevaluatepreciselytheeffectofmeteTCMandtheeffectofhepaticarterialinfusionwithChineseherbsissimilartoTACEThere

7、fore，tomakefurtherimprovementofinterventionaltherapyforPLC，thestudyofmanufacturinghi班performanceandlowtoxicityinterventionalagentespeciallyeffectivecomponentorcompoundagentofChineseherbshasbeenthoughtevenhighlyof【objecti

8、ve1ToobserveandevaluatethetherapeuticeffectivenessforPLCbyinterventionaltherapywithZTOHopetofindaneffectiveprojecttoobtainalongsurvivalrate。ImprovingtheefffeetsofPLCprolongingthesurvivaltime，andimprovingQualityoflife(QOL

9、)ofPLCpatients[methods]Retrospectivestudy95casesofmiddleadvancedstagePLChospitalizedinGuangdongprovincialHospitalofTCMfromMay1995toDecember2004。InterventionalproductisinvolvedinZTO，ZTOMicroglobule，LANXIANGXIN，andperfusio