PAF受體拮抗劑對(duì)Alzheimer病相關(guān)細(xì)胞的影響.pdf

1、中國(guó)協(xié)和醫(yī)科大學(xué)碩士學(xué)位論文PAF受體拮抗劑對(duì)Alzheimer病相關(guān)細(xì)胞的影響姓名：廖文輝申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：藥理學(xué)指導(dǎo)教師：王文杰20040501中國(guó)醫(yī)學(xué)科學(xué)院中國(guó)協(xié)和醫(yī)科大學(xué)碩士學(xué)位論文MCP1M—CSFMlP1MSMSRNFTNMDAnNOSNONOSNSAIDsPAFPDGFPOPKPGD2PGE2PGFzqPHFPLAzPPARRAGERANTESRCFROSSAPSNPSPTNF噸TRADDmonocytechemoa

2、ttractantpeptide1單核細(xì)胞趨化肽一1macrophagecolonystimulatingfactor巨噬細(xì)胞集落刺激因子macrophageinflammatoryprotein一1巨噬細(xì)胞炎性蛋白1multiplesclerosis多發(fā)性硬化癥macrophagescavengerreceptor巨噬細(xì)胞清道夫受體neurofibrillarytangle神經(jīng)原纖維性纏結(jié)N—methylD—aspartateN甲基D

3、門冬氨酸neuronalnitricoxidesynthase神經(jīng)元一氧化氮合酶Nitrogenmonoxide一氧化氮nitricoxidesynthase一氧化氮合酶Non—steroidalanti—inflammatorydrugs非甾體抗炎藥plateletactivatingfactor血小板活化因子plateletderivedgrowthfactor血小扳衍生長(zhǎng)因子prolinedirectedproteinkinase

4、脯氨酸介導(dǎo)的蛋白激酶ProstaglandinD2前列腺素D2ProstaglandinE2前列腺素E2ProstaglandinF2a前列腺素F2apairedhelicalfilaments成對(duì)螺旋細(xì)絲phosphoUpaseA2磷脂酶A2PeroxisomeProliferetoractivated過氧化物酶體增生物激活Receptor受體receptorforadvancedglycation進(jìn)行性糖化終末產(chǎn)物受體endprod

5、uctsRegulateduponactivationnormalTcellexpressedandpresumablysecretedrelativecentrifugalforce相對(duì)離心力reactiveoxygenspecies活性氧離子serumamyloidP血清淀粉樣蛋白P物質(zhì)singlenucleotidepolymorphisim單核苷酸多態(tài)性senileplaque老年斑Tumornecrosisfactora腫瘤壞