子宮內(nèi)膜異位癥患者組織中ICAM-1、VEGF及血清中sICAM-1、VEGF的表達(dá)及意義.pdf

1、石河子大學(xué)碩士學(xué)位論文子宮內(nèi)膜異位癥患者組織中ICAM1、VEGF及血清中sICAM1、VEGF的表達(dá)及意義姓名：李楠申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：婦產(chǎn)科學(xué)指導(dǎo)教師：趙霞20080501EMs患者組織中ICAN1、VEGF及血清中sICAN1、VEGF的表達(dá)及意義AbstractObjective：TostudytheexpressionofICAM1，VEGFineutopicendometrium、ectopicendometriuman

2、dtheexpressionofsICAM一1，VEGFserumofthepatientswithendometriosisToevaluatetheimportanceandrelationshipofICAM1，VEGF、slCAM一1，VEGFduringthedevelopmentinErosMethods：Collected30patientswhoweretreatedbysurgeryandconfirmedEMsbyp

3、ostoperativepathologyasthetestgroup，2549yearsold，accordingtotheinternationallyrecognizedrAFS(UnitedStatesreproductiveAssociation，1985)phasesofthephased，threecasesofStageI，l0casesPhaseII，ninecasesIIIeightcasesIV；Collected

4、30patientswhoⅥ，efetreatedbysurgeryandconfirmeduterinemyomabypostoperativepathology嬲thecontrolgroup，3350yearsoldDetectedbyimmunohistochemis仃ymethodandELISAAnalysisoftheexpressionandtheinterrelationshipsbetweenthefactorsUs

5、ingSPSSl30statisticspackageforstatisticalanalysisB曼跚ll￡：1ExpressionofICAM—l、VEGFintissues：theICAMlpositivesubstancesmainlylocalizedinthecytoplasm：Thereweresignificantdifferencesbetweenectopicendometrialgroupandthecontrol

6、group(P=O001)，ectopicgroupandthecontrolgroup(P=0037)，eutopicgroupandthecontrolgroup口=O000)TheVEGFpositivesubstancesmainlylocalizedinthecytoplasm：Thereweresignificantdifferencesbetweenectopicendometrialgroupandthecontrolg

7、roup(P=O000)，significantdifferencesbetweeneutopicgroupandthecontrolgroup(P=0037)，eutopicgroupandthecontrolgroup(P=0002)2ExpressionofslCAM一1、VEGFinserum：slCAM一1seffllmlevelofthetestgroupWashigherthanthecontrolgroup，therew

8、eresignificantdifferencesbetweentestgroupandcontrolgroup(P=0000)VEGFserumlevelofthetestgroupWashigherthanthecontrolgroup，thereweresignificantdifferencesbetweentestgroupandcontrolgroup(P=0000)3Therelationshipbetweenexpres

9、sionandclinicalstageofICAM—lintissue：botheutopicgroupandectopicgroupcomparedwiththecontrolgroupweresignificant(P005)，andstageI，IIhigherthanlII，Ⅳ(PO05)4TherelationshipbetweenexpressionandclinicalstageofVEGFintissue：botheu

10、topicgroupandectopicgroupcomparedwiththecontrolgroupweresignificant(PO05)，andstageI，IIhigherthanIII，IV(P005)5TherelationshipbetweenexpressionandclinicalstageofslCAMlinSaUlTl：botheutopicgroupandectopicgroupcomparedwiththe

11、controlgroupweresignificant(PO05)，andstageI，IIhigherthanIII，Ⅳ伊O05)6TherelationshipbetweenexpressionandclinicalstageofVEGFinserum：botheutopicgroupandectopicgroupcomparedwiththecontrolgroupweresignificant(P005)，andstageI，I

12、IhigherthanHI，Ⅳ(PO05)7TheICAMl，VEGFslCAM一1expressionoftestgroupwhetherintissuesorsc理unl8werehigherthanthecontrolgroupandtherewerecorrelationsbetweenICAM一1andVEGFslCAM一1andVEGEConclusion：1TheexpressionofICAM一1ineutopicend