黃竹清腦口服液對急性腦出血大鼠BBB指數(shù)及NSE、TNF-α表達的影響.pdf

1、Y：5G9T學院代B——』盟生nR碼——』塑些學』盟韭絲!!L镕№一陜西中醫(yī)學院ShaanxiUniversityofChineseMedicine碩士學位論文耋笪煎墮望月!避對墨董墮些墮盔塑BBB指數(shù)及NSE、TNF—q表達的影響學位申請人專業(yè)名稱申請學位類型指導教師姓名論文提交日期郭瑣中醫(yī)內(nèi)科學(腦痛專業(yè))臨床醫(yī)學碩士專業(yè)學位劉淑霞主任醫(yī)師TheEffectstoAcuteIntracerebraIHemorrhageRats，BB

2、BIndex，ExpressNSEandTNF—Q，afterTakingHuangZhuQingNaoOraILinguidABSTRACTObjective：TodiscusstheeffectstoAcuteIntracerebralHemorrhagerats，blood—brainbarrierindex，expressneuron—specificenolaseinandtumornecrosiSfactor，afterta

3、kingHuangZhuQingNaoOralLiquid，SOastoprovidetheexperimentalbaseforthetreatmentinclinicMethods：Randomlydivided60SDratsinto6groups，theyare：BlankComparisonGroup，ModelGroup，NimodipineGroup，Small，MediumandLargeDoseHuangZhuOing

4、NaoOralLiquidGroupsExceptBlankGroup，theratsinother5groupsareinjectedtheirbloodonbrainswithsolidpositionerandbuildmodels，atthesametime，theratsinBlankGroupareinjectednothingAfter12hours，accordingtoBedersonandSOon’snervedef

5、ectsgradingstandards(slightlymodified)，donervefunctionaldefectgradingfortheratsineverygroupTheanimalsget1，2and3marksarechosentodothisexperiment，andthen，begintolavagestomachonceadayAfter7days，collectspecimen：andapplybromo

6、cresolgreenmethodtoexaminecerebrospinalfluidandbloodserumalbumin：andapplyImmunochemistryMethodtoexamineneuron—specificenolaseandtumornecrosiSfactor，pleasetakethetheinstructiononthereagentboxasreferenceforthespecificwaysR

7、esults：1Alltheanimalshavesymptomsofperipheralneuropathyafterforminghematomainrats’brains：2Comparewithblankgroup，BBBindex，NSEandTNF—Qinbraintissueofmodelgroupisobviouslygettinghigher(PO01)，whichmeansthesuccessofbuildingmo