一種改進的腫瘤基因表達數(shù)據(jù)聚類分析模型.pdf

1、上海大學(xué)碩士學(xué)位論文一種改進的腫瘤基因表達數(shù)據(jù)聚類分析模型姓名：黃文佳申請學(xué)位級別：碩士專業(yè)：計算數(shù)學(xué)指導(dǎo)教師：王翼飛201005012010上海大學(xué)碩士學(xué)位論文AbstractThetechnologyofGenechipsisaplatformforanalysisofhi曲throughputgeneexpressiondataTheanalysisofthegeneexpressiondatahasbeenappliedinma

2、nyareassuchasbiomedicineresearch，diagnosisofdiseaseanddrugscreeningButintheprocessofanalyzingthegeneexpressiondata，thereexistsafewproblemssuchasthegeneexpressdataoftenpollutedbynoise；thetraditionalmethodscan’treducenoise

3、perfectly；usingthetraditionalmethodsCan’tselecttheSpecificexpressedGeneseffectivel)：AllofthesemadethesampleclusteringaccuracynothighenoughwhenweclusteredthecompletegeneexpressdataTosolvetheseproblems，thispaperestablished

4、amodifiedmodelofclusteringanalysisoftumorgenedataexpressionThismodelcombinedthemethodsofinformationextractionwavelettransform，thetwo—wayclusteringanalysisintotogethertoanalyzegeneexpressdatascientificallyThroughthismodel

5、wecouldreducethenoiseofthegeneexpressiondataandincreasetheaccuracyrateofsamplesclassifyWeapplythemodelintotheanalysisofthegeneexpressiondataofcolon，wefindsomemeaningfulSpecificexpressedGenesandachievedagoodsampleclusteri