Non Dipper Hypertension and Its Correlated Factors with Type 2 Diabetes.pdf

1、Non-dipping of nocturnal hypertension is common inpeople with type 2 diabetes and is associated with increased riskof cardiovascular morbidity and mortality. This study aimed to identify thefactors associated with noct

2、urnal non-dipping of HT in people with type 2 diabetes.Methods：Data were obtained from 50 people with type 2 diabeteswho had undergone ambulatory BP (blood pressure) monitoring. Dipperswere defined as those with a systol

3、ic night-time BP dip over 15％. Allstatistical analyses were performed using SPSS version 11.0 for Windows.Normally distributed data were analysed using a non-paired Students t-test,and non-parametric tests were used for

4、data with a skewed distribution.Chi-squared tests were used for discontinuous variables. The results wereadjusted for age using binary logistic regression, using non-dipping statusas the dependent variable.Results：No sig

5、nificant differences were seen between the meanday-time systolic BP in the dipping (145.8 mmHg) and the non-dipping(145.0 mmHg) groups (p=0.88). Non-dippers were significantly older(p<0.0001)with a higher prevalence of a

6、lbuminuria (p=0.003) and ofmacrovascular disease (p=0.008) when compared with the dipping group.After adjustment for age, albuminuria remained more prevalent within thenon-dipping group (p=0.007). There was no significa

7、nt difference inglycaemic control, type of diabetes treatment, smoking status, or genderbetween the groups.Conclusion：Albuminuria is strongly associated with non-dipping ofnocturnal BP in people with type 2 diabetes. An